Section: 
Science articles
Science articlesLong-term microstructure changes of the central part of auditory system in patients with chronic ear pathology before and after hearing improving ear surgery
F. A. Syroezhkin (1), V. V. Dvoryanchikov (1), A. G. Trufanov (1), L. V. Voronkov (1), D. N. Borisov (1)
(1) Military Medical Academy named after S. M. Kirov, Saint Petersburg, 194044, Russia
UDK: 616.28–008.1–008.5:616.831–07.572
DOI: https://doi.org/10.18692/1810-4800-2016-3-108-114
ABSTRACT
The objective of the study of specific features of microstructural changes of the central part of auditory system in 17 patients with chronic ear diseases before and after ear surgery by means of MR-morphometry and diffusion tensor tractography. The obtained data of the volume of the grey matter and the thickness of cortex of definite structures related to auditory information processing have been compared with the results of 20 healthy persons. Besides, the study of the functional state of the airways in terms of fractional anisotropy index has been performed. The obtained changes in the grey and white matter of brain prove the microstructural reorganization in the central part of auditory system in hearing-impaired patients. It has been found out that the main changes concerned the increase of the volume of the grey matter and the thickness of cortex in the areas of hearing fields of the right hemisphere (superior temporal sulcus and gyrus). The revealed structural transformation phenomena might result from the long-term sensory deprivation related to hearing loss. The follow-up comparison made in 12 months after the ear surgery revealed the signs of restoration of morphometric values in a number of structures of the central part of auditory system.
Publication date:
30.05.2016
Keywords:
hearing loss, otosclerosis, chronic otitis, stapedoplasty, tympanoplasty, voxelbased morphometry, diffusion tensor magnetic resonance imaging, Freesurfer. For citation:
Syroezhkin F. A., Dvoryanchikov V. V., Trufanov A. G., Voronkov L. V., Borisov D. N. Long-term microstructure changes of the central part of auditory system in patients with chronic ear pathology before and after hearing improving ear surgery. Rossiiskaya otorinolaringologiya. 2016;3:108-114. https://doi.org/10.18692/1810-4800-2016-3-108-114