Section: 
Science articles
Science articlesLipid metabolism indices as the markers of risk of sensorineural hearing loss development
A. M. Kaneva (1), S. G. Boiko (2), N. N. Potolitsyna (1), O. E. Kudryavykh (3), A. M. Kudryavykh (3), E. R. Boiko (1), Yu. K. Yanov (3)
(1) Federal State Budgetary Institution of Science Komi Institute of Physiology of Scientific Centre of Ural Branch of the Russian Academy of Sciences, Syktyvkar, Russia
(2) Good Hearing Center Istok Audio Treiding LLC, Syktyvkar, Russia
(3) Federal State Budgetary Institution “Saint Petersburg Research Institute of Ear, Throat, Nose and Speech”, Ministry of Health of the Russian Federation, Saint Petersburg, Russia
UDK: 616.28-009:577.125
DOI: https://doi.org/10.18692/1810-4800-2017-2-48-54
ABSTRACT
The complex analysis of lipid metabolism in patients with sensorineural hearing loss (SNHL) has shown that the auditory dysfunction is associated with the increase of the lipid profile atherogenicity. However, there were no significant differences in conventional lipid metabolism parameters (total cholesterol, triglycerides, high density lipoprotein cholesterol (HDL-C)) between the patients with SNHL and the control group subjects. The higher values of apolipoprotein (apo) B/apoA-I ratio, atherogenic index of plasma (AIP) and atherogenic index (ATH index) in patients with SNHL indicate the increase of lipid profile atherogenicity. The atherogenic index (ATH index) has high predictive power of SNHL risk.
Publication date:
06.05.2017
Keywords:
sensorineural hearing loss, lipid metabolism, apoB/apoA-I ratio, atherogenic index of plasma (AIP), atherogenic index (ATH index). For citation:
Kaneva A. M., Boiko S. G., Potolitsyna N. N., Kudryavykh O. E., Kudryavykh A. M., Boiko E. R., Yanov Yu. K. Lipid metabolism indices as the markers of risk of sensorineural hearing loss development. Rossiiskaya otorinolaringologiya. 2017;2:48–54. https://doi.org/10.18692/1810-4800-2017-2-48-54