Section: 
Science articles
Science articlesMicrobiota of the tympanic cavity in the patients with chronic suppurative otitis media
S. Yu. Babaev (1), A. A. Novozhilov (2), T. E. Abubakirov (2), N. N. Mitrofanova (3), E. A. Kozarenko (1), Shakhov A. V. (1), (2)
(1) Privolzhskiy Research Medical University, 603005, Nizhny Novgorod, Russia
(2) Privolzhskiy District Medical Center of FMBA of Russia, 603005, Nizhny Novgorod, Russia
(3) Penza State University, 440026, Penza, Russia
UDK: 616.284-002.3+616.284.4-008.87
DOI: https://doi.org/10.18692/1810-4800-2019-3-22-26
ABSTRACT
The objective of the work is to study the environmental and epidemiological features of the tympanic cavity microbiota in patients with chronic suppurative otitis media (ChSOM). The authors conducted an environmental and epidemiological study, which included the isolation and identification of microorganisms using bacterioscopic, cultural and biochemical methods. The material samples were taken from 66 patients with various forms of chronic suppurative otitis media in remission (54 with chronic mesotympanitis and 12 with chronic epimesotympanitis). The main microorganisms isolated from the tympanic cavity were S. epidermidis, P. aeruginosa, S. aureus, and Enterococcus faecium. During the study of the qualitative composition of microflora colonizing the tympanic cavity in the patients with chronic suppurative otitis media, the monocultures and associations, including 2-3 types of microorganisms, were isolated. The resulting microbial associations have a low coefficient of environmental affinity, the predominant relations between them are antagonistic. S. epidermidis is resistant to benzylpenicillin, roxithromycin and azithromycin; P. aeruginosa was characterized by resistance to carbenicillin, cefepime and amoxicillin. S. aureus had the highest resistance to benzylpenicillin, ampicillin. Among the Enterococcus faecium bacteria, the highest percentage of resistance was observed to oxacillin, amikacin and roxithromycin.
Publication date:
18.06.2019
Keywords:
chronic purulent otitis media, microbiota, tympanic cavity. For citation:
Babaev S. Yu., Novozhilov A. A., Abubakirov T. E., Mitrofanova N. N., Kozarenko E. A., Shakhov A. V. Microbiota of the tympanic cavity in the patients with chronic suppurative otitis media. Rossiiskaya otorinolaringologiya. 2019;18(3):22–26. https://doi.org/ 10.18692/1810-4800-2019-3-22-26