Section: 
School of pharmacotherapy
School of pharmacotherapyHypertonic seawater solution as an alternative to topical decongestants
T. I. Garashchenko (1), (2), O. V. Karneeva (1), (2), G. D. Tarasova (1), A. S. Tulina (1), A. S. Yunusov (1), L. I. Il’enko (3), M. V. Garashchenko (3), Ya. M. Sapozhnikov (1)
(1) Scientific and Clinical Center of Otorhinolaryngology, Moscow, 123182, Russia
(2) Department of Otorhinolaryngology, Faculty of Additional Vocational Education, Pirogov Russian National Research Medical University, Moscow, 117197, Russia
(3) Department of Hospital Pediatrics N 2 of the Faculty of Pediatrics, Pirogov Russian National Research Medical University, Moscow, 117197, Russia
UDK: 616.211-002.1-053.2:615.225.1
DOI: https://doi.org/10.18692/1810-4800-2019-5-106-114
ABSTRACT
The authors performed a comparative study of the efficacy and safety of irrigation elimination therapy (IET) a hypertonic solution of sea water (and other means-Forte) and a topical decongestant 0.1% solution of Xylometazoline (0.1% Glycine Ksilo) in the treatment of children with acute infectious rhinosinusitis. The article presents the results of evaluation of the dynamic clinical picture and the data of objective study of anterior active rhinomanometry (PARM) using the rhinomanometer ATMOS 300 from the moment of entering the study to the 7th day of treatment. Obtained by the authors of the subjective (clinical) and objective (results of PARM) data to prove the comparative efficacy and high safety of the IEP of hypertonic saline solution in comparison with the use of topical vasoconstrictor for acute infectious rhinosinusitis in children.
Publication date:
25.10.2019
Keywords:
acute infectious rhinosinusitis, irrigation-elimination therapy, hypertonic salt solution, topical decongestants, childhood. For citation:
Garashchenko T. I., Karneeva O. V., Tarasova G. D., Tulina A. S., Yunusov A. S., Il’enko L. I., Garashchenko M. V. Hypertonic seawater solution as an alternative to topical decongestants. Rossiiskaya otorinolaringologiya. 2019;18(5):106–114. https://doi.org/10.18692/1810-4800-2019-5-106-114