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Science articles
Science articlesThe effect of herpesviral infection on the postsurgical period after cochlear implantation in children
Yu. S. Preobrazhenskaya (1), M. V. Drozdova (1), V. E. Kuzovkov (1), E. V. Tyrnova (1)
(1) Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013, Russia
UDK: 616.283.1-089.873:616.284-003.2]-053.2
DOI: https://doi.org/10.18692/1810-4800-2019-6-53-58
ABSTRACT
The authors conducted a clinical and audiological examination of 100 children with high degree of sensorineural hearing loss and indications for cochlear implantation. In the process of the study, they calculated the frequency of postsurgical complications. Two comparative groups were formed. The first group included 27 patients with complicated postsurgical period. The second group included 73 patients without complications. To clarify the specific features of hemostasis, the children after the surgery underwent the analysis of laboratory and diagnostic tests (of the 1st and 2nd level). In the process of the study, the patients of the two study groups underwent serological and molecular genetic examination for herpesviral infections (Epstein Barr virus, cytomegalovirus). The authors analyzed the correlation between the development of post-surgical complications and the persistent herpesviral infection. In the group of patients with postsurgical complications herpesviral infection was diagnosed in 77.8% (n = 21) of cases, in the group without complications – only in 39.7% (n = 29) of cases. We have confirmed the research data that surgical injury in combination with general anesthesia can cause reactivation of persistent herpesviral infection. The active infectious process markers were found in the first group in 14.8% (n = 4) of cases. The persistent herpesviral infection could trigger the development of both inflammatory and non-inflammatory complications after surgical treatment.
Publication date:
11.12.2019
Keywords:
sensorineural hearing loss, cochlear implantation, cytomegalovirus, Epstein–Barr virus, children. For citation:
Preobrazhenskaya Yu. S., Drozdova M. V., Kuzovkov V. E., Tyrnova E. V. The effect of herpesviral infection on the postsurgical period after cochlear implantation in children. Rossiiskaya otorinolaringologiya. 2019;18(6):53–58. https://doi.org/10.18692/1810-4800-2019-6-53-58