Section: 
From practice
From practiceCase study of early diagnostics of larynx and hypopharynx cancer relapse
N. A. Daikhes (1), V. V. Vinogradov (1), A. I. Gafurova (1), S. S. Reshul’skii (1), A. S. Korobkin (1), A. M. Khabazova (2)
(1) Scientific and Clinical Center of Otorhinolaryngology, Moscow, 123182, Russia
(2) Pirogov Russian National Research Medical University, Moscow, 117997, Russia
UDK: 616.22-006.61-059-089.87
DOI: https://doi.org/10.18692/1810-4800-2019-6-97-103
ABSTRACT
By incidence, larynx cancer occupies the leading position among malignant tumors of ENT organs. In the structure of the total incidence of malignant tumors, larynx cancer amounted to 1.13% in 2017, but the absolute number of patients with first diagnosed larynx cancer continues to grow, and the majority of the patients are admitted for treatment at stage III and IV of the disease. The treatment of patients with stage III and IV of laryngeal cancer can be either combined or complex. Laryngectomy is the prevailing surgical intervention resulting in profound disability and social maladjustment of patients, which predisposes to the search for less traumatic treatment methods. The frequency of continued growth and recurrence at the late stages of the tumor process after radiation and chemoradiation therapy necessitates the development of highly informative methods of locoregional control. The advanced diagnostic methods allow to suspect a relapse of the disease, however, for its verification, it is necessary to perform a histological examination of the biopsy material. In this regard, US-controlled interventional techniques are of particular importance as a safe, easily reproducible and cost-effective way of obtaining morphological verification, even in outpatient conditions. Percutaneous harpoon biopsy under the ultrasound navigation control with subsequent morphological verification is an invasive method providing histological verification of the diagnosis, which is necessary to determine the approach to the further treatment applicable in the outpatient conditions, due to the minimal number of complications.
Publication date:
11.12.2019
Keywords:
laryngeal cancer, malignant tumors, relapse, percutaneous harpoon biopsy, oncology. For citation:
Daikhes N. A., Vinogradov V. V., Gafurova A. I., Reshul’skii S. S., Korobkin A. S., Khabazova A. M. Case study of early diagnostics of larynx and hypopharynx cancer relapse. Rossiiskaya otorinolaringologiya. 2019;18(6):97–103. https://doi.org/10.18692/1810-4800-2019-6-97-103