Section: 
Science articles
Science articlesFactors affecting the early postoperative period of cochlear implantation
Yu. S. Preobrazhenskaya (1), M. V. Drozdova (1), S. B. Sugarova (1), D. D. Kalyapin (1), S. N. Larionova (1)
(1) Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013, Russia
UDK: 616.283.1-089.843-089.168.1-053.2
DOI: https://doi.org/10.18692/1810-4800-2020-6-57-63
ABSTRACT
Persistence of viral infections ((Epstein–Barr virus (EBV), cytomegalovirus (CMV)) contributes to the development of inflammatory pathology of the upper respiratory tract, as well as dystrophic processes in hepatocytes. The impact of this fact on the early postoperative period during cochlear implantation remains poorly understood. A clinical and audiological examination of 100 children with high-grade sensorineural hearing loss was performed. Within the framework of the work, a serological and molecular genetic examination of patients for herpesvirus infections (Epstein–Barr virus, cytomegalovirus) was performed. Two comparison groups are highlighted. The first group included 58 patients with detected latent infections. In the second group 42 patients did not have serological and molecular genetic markers of infection with herpesvirus infection. There is evidence in the literature that surgical trauma combined with general anesthesia can cause reactivation of persistent herpesvirus infection. In 4% (n = 4), markers of an active infectious process were detected. The analysis of the course of the postoperative period in children in two study groups after cochlear implantation was performed. In the hemostatic system, hypocoagulation disorders were found in a number of children. Persistent herpesvirus infection can be a trigger for the development of both inflammatory and non-inflammatory complications after surgical treatment.
Publication date:
08.12.2020
Keywords:
sensorineural hearing loss, cochlear implantation, cytomegalovirus, Epstein–Barr virus, children, hemostasis.
For citation:
Preobrazhenskaya Yu. S., Drozdova M. V., Sugarova S. B., Kalyapin D. D., Larionova S. N. Factors affecting the early postoperative period of cochlear implantation. Rossiiskaya otorinolaringologiya. 2020;19(6):57–63. https://doi.org/10.18692/1810-4800-2020-6-57-63