Section: 
From practice
From practiceModern approaches to assessing motor activity of epithelial cilia of upper respiratory tract
A. L. Klochikhin (1), V. V. Byrikhina (1)
(1) Yaroslavl State Medical University, Yaroslavl, 150000, Russia
UDK: УДК 616.216.2:616.216.4-006.81
DOI: https://doi.org/10.18692/1810-4800-2022-6-110-113
ABSTRACT
Malignant tumors of the mucous membrane of the paranasal sinuses and nasal cavity are quite rare, which is from 0,2 to 1,3% of all malignant tumors of the head and neck. Melanoma of the mucous membrane of the paranasal sinuses and nasal cavity is less than 5% of all neoplasms of this localization and less than 1% of all melanomas. Melanoma is one of the most dangerous, often recurrent, metastatic malignant tumors. More often, melanoma occurs in the maxillary sinus, less often it is diagnosed in the frontal sinus. The average age of patients with melanoma is 58,7 years. Men and women get sick almost equally often. The duration of the disease ranges from several months to 3–5 years. The prognosis for melanoma of the mucous membranes is unfavorable, with a three-to-five-year survival rate of 10–15%. Clinically, most often in the early stages of the development of paranasal sinus melanoma, the disease is asymptomatic. Possible manifestations depend on the location of the tumor germination. Treatment of melanoma of the paranasal sinuses and nasal cavity depends on the stage of the disease.
Publication date:
21.12.2022
Keywords:
tumor, melanoma, paranasal sinuses, genetic change, intracellular signaling pathways. For citation:
Klochikhin A. L., Byrikhina V. V. Case report of rare melanoma of inferior part of frontal sinus and ethmoidal labyrinth with transition to orbital fat. Rossiiskaya otorinolaringologiya. 2022;21(6):110-113. https://doi.org/10.18692/1810-4800-2022-6-110-113