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Science articles
Science articlesPrevalence of asymptomatic carriage of methicillin-resistant Staphylococcus spp. On mucous membrane of nasal cavity and oropharynx
E. V. Shugakova (1), Yu. A. Pimenova (1), A. B. Kiselev (1), A. N. Evstropov (1)
(1) Novosibirsk State Medical University, Novosibirsk, 630091, Russia
UDK: УДК 616.327.2+616.31/.32:576.851.252
DOI: https://doi.org/10.18692/1810-4800-2023-2-57-60
ABSTRACT
Staphylococci are widely distributed in the environment. Most species of the genus Staphylococcus are opportunistic resident representatives of the human and animal microbiota, capable of causing diverse clinical manifestations of varying severity. The situation is aggravated by the widespread distribution of representatives of the genus Staphylococcus, which are resistant to methicillin – the first semi-synthetic penicillin – and are causative agents of community-acquired infections posing a danger to immuno-compromised people. The purpose of our study was to identify methicillin-sensitive and methicillin-resistant strains of Staphylococcus spp. on the mucous membrane of the nasal cavity and oropharynx by polymerase chain reaction. The study involved 588 people who, as part of their professional activities, should be examined for carriage of Staphylococcus aureus in the nasopharynx. As a result of the study, staphylococcus DNA was detected in 273 (46.42%) of the subjects, and methicillin-resistant strains predominated, they were detected in 227 (83.15%) people. Among them, DNA of methicillin-resistant coagulase-negative Staphylococcus spp. was found in 148 (54.21%) people, a combination of different types of methicillin-resistant staphylococci, including methicillin-resistant S. aureus and methicillin-resistant coagulase-negative Staphylococcus spp., was detected in 53 (19.41%) subjects, DNA of methicillin-resistant S. aureus in monoculture was detected in 26 (9.52%) people. DNA of methicillin-sensitive S. aureus was found in 46 (16.84%) people.
Publication date:
24.04.2023
Keywords:
nasal cavity, oropharynx, staphylococci, adult patients. For citation:
Shugakova E. V., Pimenova Yu. A., Kiselev A. B., Evstropov A. N. Prevalence of asymptomatic carriage of methicillin-resistant Staphylococcus spp. On mucous membrane of nasal cavity and oropharynx. Russian Otorhinolaryngology. 2023;22(2):57-60. https://doi.org/10.18692/1810-4800-2023-2-57-60