Section: 
Science articles
Science articlesComprehensive treatment of chronic pathology of larynx in Sjögren’s disease
N. A. Daikhes (1), (2), N. M. Kotel’nikova (1), O. V. Karneeva (1), (2), T. I. Garashchenko (1), (2), A. V. Gertsen (1)
(1) National Medical Research Center for Otorhinolaryngology of the Federal Medico-Biological Agency of Russia, Moscow, 123182, Russia, (2) Pirogov Russian National Research Medical University, Moscow, 117997, Russia
UDK: УДК 616.316-008.2:616.22-002.2
DOI: https://doi.org/10.18692/1810-4800-2023-5-28-38
ABSTRACT
Issues of voice quality and health, as the main means of communication, are becoming increasingly relevant. One of the causes of dysphonia is Sjögren’s disease. Progressive dryness of the mucous membrane of the upper respiratory tract, autoimmune disorders lead to the development of chronic pathology of the vocal apparatus. Treatment methods traditionally used for chronic pathology of the larynx do not achieve high and lasting improvement in voice quality in patients with Sjögren’s disease. The purpose of this study was to evaluate the effectiveness of the developed method of complex treatment of chronic laryngeal pathology in Sjögren’s disease. 46 patients with voice disorders associated with Sjögren’s disease were examined and treated. The patients were divided into two groups. Group I (20 patients) received treatment traditionally used for chronic laryngitis. In group II (26 patients), complex treatment was supplemented by three-stage aerosol therapy of the mucous membrane of the upper respiratory tract with saline solution sounded by low-intensity ultrasound, intranasal application of a drug containing hyaluronic acid, and light therapy to the larynx area. Based on an assessment of the dynamics of patient complaints, data from videolaryngostroboscopy, acoustic analysis of the voice, and the results of a questionnaire using a visual analogue scale for the severity of dryness of the mucous membrane of the upper respiratory tract, a comparative analysis of the results of therapy demonstrated a more striking and lasting improvement in the clinical and functional state of the larynx in patients of group II. Thus, the developed method of complex treatment of chronic pathology of the larynx in Sjögren’s disease, including three-stage aerosol therapy of the mucous membrane of the upper respiratory tract with saline solution sounded by low-intensity ultrasound, light therapy to the larynx area, and a topical preparation containing hyaluronic acid, allows achieving a pronounced positive effect with an aftereffect for 5 months.
Publication date:
25.10.2023
Keywords:
Sjögren’s disease, chronic laryngitis, bamboo vocal fold nodules, dysphonia, voice disorders, videolaryngostroboscopy, hoarseness, light therapy, aerosol therapy, laser therapy, low-intensity ultrasound, dry syndrome. For citation:
Daikhes N. A., Kotel’nikova N. M., Karneeva O. V., Garashchenko T. I., Gertsen A. V. Comprehensive treatment of chronic pathology of larynx in Sjögren’s disease. Russian Otorhinolaryngology. 2023;22(5):28-38. https://doi.org/10.18692/1810-4800-2023-5-28-38