Section: 
School of pharmacotherapy
School of pharmacotherapyMicrobiocenosis of upper respiratory airway as a risk factor for local complications during the postoperative period after resection of the larynx
E. V. Shugakova (1), V. A. Chaukina (1), A. B. Kiselev (1), A. S. Avtushko (1), V. V. Kiselev (1)
(1) The Budget Educational Institution of Higher Vocational Education Novosibirsk State Medical University of the Ministry of Healthcare of the Russian Federation, Novosibirsk, Russia
UDK: 576.8.073.3:616.22–006.6–089.168.1-06
DOI: https://doi.org/10.18692/1810-4800-2017-1-154-158
ABSTRACT
Unadequate antibiotic therapy, the low level of hemoglobin in erythrocytes, concomitant somatic diseases are confirmed to complicate early postoperative period for oncology patients. Authors suggest the idea, that pathologic mucosal microbiocenosis in the upper respiratory airway stipulates local postoperative complication after larynx resection in cases of laryngeal cancer.
The authors proved that postoperative complications occur, because virulent strains of gram-positive microorganisms, both in monoculture and in association with Candida fungi are predominant in the mucosal microbiocenosis of upper respiratory airway. Authors have confirmed in clinic-based studies that nonpathologic microorganisms as indigenous microflora can reduce probability of local complications duringearly postoperative period after larynx resection in cases of laryngeal cancer.
It is revealed that postoperative complications associated pathologic mucosal microflora with the presence of anisocytosis of red blood cells and do not depend on the level of hemoglobin in the erythrocyte before the surgery.
Publication date:
10.02.2017
Keywords:
laryngeal cancer, postoperative complications, erythrocyte, microbiocenosis of upper respiratory airway. For citation:
Shugakova E. V., Chaukina V. A., Kiselev A. B., Avtushko A. S., Kiselev V. V. Microbiocenosis of upper respiratory airway as a risk factor for local complications during the postoperative period after resection of the larynx. Rossiiskaya otorinolaringologiya. 2017;1:154–158. https://doi.org/10.18692/1810-4800-2017-1-154-158