Section: 
Science articles
Science articlesThe use of leukocyte-rich platelet-rich fibrin in the middle ear surgery
V. G. Borodulin (1), A. N. Bervinova (1)
(1) Federal State Budgetary Educational Institution of Higher Vocational Education Pavlov First Saint Petersburg State Medical University, Saint Petersburg, Russia
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DOI: https://doi.org/10.18692/1810-4800-2018-1-21-24
ABSTRACT
The article presents the results of the use of leukocyte-rich platelet-rich fibrin (L-PRF) in the middle ear surgery. L-PRF is a platelet concentrate on the matrix of fibrin prepared of the patient’s blood by centrifugation. We have studied two groups of patients. Group 1 included 50 patients at the age of 19 to 67 years, all the patients had undergone tympanoplasty. Group 2 consisted of 23 patients at age of 22 to 62 years, all after stapedoplasty. L-PRF was used for reinforcement of neotympanic membrane during tympanoplasty and for closure of diastase between the stem of prosthesis and vestibular window during stapedoplasty. L-PRF was obtained using a standard method.
We have revealed a positive relation between the L-PRF application and the surgery outcome. The use of this material is both safe for the patient and cost-effective. The further study in this field is necessary for finding L-PRF effect and its implementation the wide application in clinical practice.
Publication date:
27.12.2017
Keywords:
chronic suppurative otitis media, otosclerosis, tympanic membrane perforation, platelet rich fibrin, tympanoplasty, stapedoplasty. For citation:
Borodulin V. G., Bervinova A. N. The use of leukocyte-rich platelet-rich fibrin in the middle ear surgery. Rossiiskaya otorinolaringologiya. 2018;1:21–24. https://doi.org/10.18692/1810-4800-2018-1-21-24