Section: 
Science articles
Science articlesNasal cycle and its practical application in otorhinolaryngology
O. V. Fedoseeva (1)
(1) State Budget Educational Institution of Higher Vocational Education Yaroslavl State Medical University of the Ministry of Healthcare of the Russian Federation, Yaroslavl, Russia
UDK: 616.211-08:613.84
DOI: https://doi.org/10.18692/1810-4800-2018-3-92-97
ABSTRACT
The nasal cycle (NC) plays a special role in the operation of ciliated epithelium and its protection from exposure of various substances, including tobacco smoke and medications. The objective of the work is to study the possibility of practical application of rhinoflowmeter Rinotsykl by the example of studying the NC changes in smokers and in patients suffering from acute rhinosinusitis (ARS). The task of the study was to conduct 24-hour registration of NC in active and passive smokers, registration of NC in the patients with ARS over 16–18 hours with a single use of topical decongestants and glucocorticosteroids (GCS) for treatment and the detailed analysis of the charts. Patients and methods. The authors have conducted the monitoring of the oscillations of the nasal air flow using the portable rhinoflowmeter Rinotsykl in 40 adult smokers aged 18–90 years and the monitoring of patients with ARS aged 18-71 over 16-18 hours with a single use of topical decongestants and GCS. The obtained data were processed using conventional computer program. Results. 92.5% of smokers had irregular air flow fluctuations. After topical drugs installations the relative volumetric airflow (RVAF) increased significantly in both groups of decongestants and GCS treatment. The NC fluctuation duration in the patients using decongestants increased; on the contrary, it decreased in the patients using GCS (p < 0.05). Conclusions. The prolonged rhinoflowmetry method makes it possible to conduct a continuous NC study and the detailed analysis of the changes of its indices, even insignificant ones. The inhalation of tobacco significantly reduced RVAF and resulted in the occurrence of NC acyclic intervals. Topical decongestants installations significantly improved nasal breathing, but adversely affected the RVA harmonious fluctuations cyclicity. To the contrary, using GCS with statistically significant increase of airflow and a somewhat delayed onset of action contributed to the NC stabilization.
Publication date:
31.05.2018
Keywords:
nasal cycle, rhinoflowmetry, smoking, xylometazoline, mometasone furoate. For citation:
Fedoseeva O. V. Nasal cycle and its practical application in otorhinolaryngology. Rossiiskaya otorinolaringologiya. 2018;3:92–97. https://doi.org/10.18692/1810-4800-2018-3-92-97