Section: 
School of pharmacotherapy
School of pharmacotherapyThe experience of using Frinosole in the early postoperative period in patients after endonasal endoscopic operations
A. V. Emel’yanov (1), N. I. Il’ina (2), O. V. Karneeva (3), S. A. Karpishchenko (4), I. A. Kim (3), O. M. Kurbacheva (2), N. M. Nenasheva (5), O. V. Obukhova (6), V. M. Svistushkin (7), O. P. Ukhanova (8)
(1) Mechnikov North-West State Medical University,Saint-Petersburg, Russia
(2) Institute of Immunology, Moscow, 115478, Russia
(3) National Medical Research Center of Otorhinolaryngology, Moscow, 123182, Russia
(4) Pavlov First Saint Petersburg State Medical University, Saint Petersburg, 197022, Russia
(5) Russian Medical Academy of Continuing Professional Education,Moscow, 125993, Russia
(6) Central Research Institute of Health Organization and Informatization, Moscow, 127254, Russia
(7) Sechenov First Moscow State Medical University, Moscow, 119991, Russia
(8) Stavropol State Medical University, Stavropol, 355017, Russia
UDK: 616.211-089-072.1:616.225.1
DOI: https://doi.org/10.18692/1810-4800-2020-3-100-104
ABSTRACT
The effectiveness of the drug Frinosole in the complex treatment of early postoperative changes in the nasal mucosa after endonasal endoscopic surgery was studied. It has been confirmed that during surgical trauma of the mucous membrane of the nasal cavity, inhibition of the main functions of the respiratory epithelium occurs with a sharp increase in the absorption capacity of the mucous membrane of the nasal cavity. These changes correlate with the clinical picture of the early postoperative period. The data presented indicate a high efficacy of the drug in complex postoperative treatment and make it possible to recommend it for wider use in order to minimize the duration of the postoperative healing stages and prevent possible complications associated with excessive granulation and scarring of the nasal mucosa in the surgical areas.
Publication date:
25.06.2020
Keywords:
Frinosole, postoperative period, inflammation, treatment.
For citation:
Mashkova T. A., Mal’tsev A. B. The experience of using Frinosole in the early postoperative period in patients after endonasal endoscopic operations. Rossiiskaya otorinolaringologiya. 2020;19(3):100–104. https://doi.org/10.18692/1810-4800-2020-3-100-104