Section: 
Science articles
Science articlesUse of allogeneic cartilage in reconstruction surgery of laryngeal and tracheal stenosis
E. A. Kirasirova (1), N. V. Lafutkina (1), R. F. Mamedov (1), R. A. Rezakov (1), M. I. Usova (1), S. I. Tyutina (1), E. A. Egorova (1), E. V. Kulabukhov (1)
(1) Sverzhevsky Research Clinical Institute of Otorhinolaryngology Department of Healthcare of the City of Moscow, Moscow, 117152, Russia
UDK: 615.466:616.22/.23-007.271-089.844
DOI: https://doi.org/10.18692/1810-4800-2021-3-33-38
ABSTRACT
This article analyzes the increasing effectiveness of extensive defects and chronic cicatricial laryngeal and tracheal stenosis treatment with the allogeneic cartilage implantation. The study included 63 patients with an age interval of 18–65 years and a disease duration from 3 months to 6 years. Radiologic, functional and endoscopic investigations were carried out, after which the patients underwent laryngotracheoplasty using allogeneic cartilage, which has low antigenicity, affects the growth of the recipient’s tissues and prevents scarring. After the discharge, a dynamic outpatient observation was carried out: 2 times a week – 10 days; once a week – 21 days, once a month - 6 months. The study revealed that a differentiated approach to the treatment of patients with stenosis of the laryngeal-tracheal complex using the allogeneic cartilage made it possible to fully rehabilitate of 59 (94%) of 63 patients (100%). Only 4 (6%) patients had partial resorption or rejection of implanted cartilaginous allografts that led to the failure of the laryngeal and tracheal walls in the late postoperative period. The use of the allogeneic cartilage implantation in reconstructive surgery has proved to be highly effective in the laryngeal and tracheal framework defects, resulted from prolonged stenosis, major surgical interventions, and trauma.
Publication date:
07.06.2021
Keywords:
allogeneic cartilage, laryngeal-tracheal complex defect, implant material, laryngotracheoplasty.
For citation:
Kirasirova E. A., Lafutkina N. V., Mamedov R. F., Rezakov R. A., Usova M. I., Tyutina S. I., Egorova E. A., Kulabukhov E. V. Use of allogeneic cartilage in reconstruction surgery of laryngeal and tracheal stenosis. Rossiiskaya otorinolaringologiya. 2021;20(3):33-38. https://doi.org/10.18692/1810-4800-2021-3-33-38