Section: 
School of pharmacotherapy
School of pharmacotherapyDoes ectoin affect release of allergens from pollen of wind-blown plants?
T. M. Zheltikova (1), I. G. Akhapkina (1), M. A. Mokronosova (1)
(1) Mechnikov Research Institute of Vaccines and Serums, Moscow, 105064, Russia
UDK: 576.8.097.2
DOI: https://doi.org/10.18692/1810-4800-2021-6-109-114
ABSTRACT
The effect of ectoin on the release of allergens from pollen grain of wind-blown plants was studied. The birch, alder, hazel, timothy, and orchard grass pollen grains were used for this experiment. Enzyme-linked immunosorbent assay (ELISA) and morphological examination of birch pollen grains utilizing the light microscope were used. The findings indicated that ectoin does not promote the allergen release from pollen. Thus, ectoin not only improves the barrier function of the nasal mucosa and washes pollen from the nasal cavity, but also does not disturb their integrity and does not affect the release of allergens.
Publication date:
27.12.2021
Keywords:
ectoin, pollen of wind-blown plants, pollen allergens. For citation:
Zheltikova T. M., Akhapkina I. G., Mokronosova M. A. Does ectoin affect release of allergens from pollen of wind-blown plants? Rossiiskaya otorinolaringologiya. 2021;20(6):109-114. https://doi.org/10.18692/1810-4800-2021-6-109-114