Section: 
Science articles
Science articlesRisk factors for progression of chronic tonsillitis
V. V. Dvoryanchikov (1), V. G. Mironov (2), A. S. Kim (3), A. G. Sinel’nikova (3), S. A. Bannikov (4), R. I. Sinel’nikov (4), O. I. Bachurina (5)
(1) Saint Petersburg Research Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013, Russia, (2) Kirov Military Medical Academy, Saint Petersburg, 194044, Russia, (3) Rostov State Medical University, Rostov-on-Don, 344000, Russia, (4) Regional Advisory and Diagnostic Centre, Rostov-on-Don, 344000, Russia, (5) Rostov Regional Clinical Hospital, Rostov-on-Don, 344015, Russia
UDK: УДК 616.322-002.2-039.36
DOI: https://doi.org/10.18692/1810-4800-2023-6-24-30
ABSTRACT
Chronic tonsillitis is considered one of the most common nosologies in the structure of ENT diseases. According to WHO, chronic tonsillitis appears to be a general medical issue, which is of particular interest to both otorhinolaryngologists and infectious disease specialists, therapists, rheumatologists, and pediatricians. Patients and methods. 100 patients with chronic tonsillitis of the toxic-allergic form who were hospitalized were studied. The patients were divided into 2 groups: the first (comparison, n = 50), with a mild form of chronic tonsillitis; the second (main, n = 50), with a severe form. Treatment is conservative. The research methods included a complex of clinical, laboratory, and instrumental examinations. The results showed that in children suffering from chronic tonsillitis of the toxic-allergic form significant changes occur in the homeostasis system, in the pathogenesis of which endogenous intoxication, abnormalities of the immune system, hepatic depression, and blood coagulation disorders play an important role. The latter are the main triggers of the disease leading to worsening of the disease. It was revealed that all these changes are associated with the form of the disease. In patients with a severe form of the disease, these changes were significantly greater than in patients with a mild form. Conclusions. It was shown that the influence of standard therapy used for chronic tonsillitis of the toxic-allergic form turned out to be therapeutically effective in mild forms, and ineffective in severe ones. Therefore, it is necessary to find additional measures to increase the overall effectiveness of treatment for severe chronic tonsillitis.
Publication date:
25.12.2023
Keywords:
tonsillitis, endotoxicosis, immunity, hemostasis, liver. For citation:
Dvoryanchikov V. V., Mironov V. G., Kim A. S., Sinel’nikova A. G., Bannikov S. A., Sinel’nikov R. I., Bachurina O. I. Risk factors for progression of chronic tonsillitis. Russian Otorhinolaryngology. 2023;22(6):24-30. https://doi.org/10.18692/1810-4800-2023-6-24-30