Section: 
Science articles
Science articlesClinical and immunological changes in the nasal mucosa of patients with chronic viral hepatitises
A. Z. Mestnikova (1), S. A. Artyushkin (1), I. A. Samusenko (2), A. A. Kalashnikova (2)
(1) North-Western State Medical University named after I. I. Mechnikov, Saint Petersburg, 191015, Russia (2) The Nikiforov Russian Center of Emergency and Radiation Medicine, Saint Petersburg, 194044, Russia
UDK: 616-022.6 : 616.213.6
DOI: https://doi.org/10.18692/1810-4800-2016-2-73-80
ABSTRACT
The problem of nasal bleeding in patients with liver disease is of high concern. The complex research of biopsy materials of the nasal mucosa of patients with chronic viral hepatitises B and C, including the study of viral antigens, evaluation of morphological mucosa changes, estimate of lymphocyte subpopulation composition makes it possible to suggest applicable mechanisms causing nosebleeds.
Publication date:
31.03.2016
Keywords:
extrahepatic hepatitis manifestations, Tkiller cells, Thelper cells, NS3 protein, HBsAg, mucosa metaplasia. For citation:
Mestnikova A. Z., Artyushkin S. A., Samusenko I. A., Kalashnikova A. A. Clinical and immunological changes in the nasal mucosa of patients with chronic viral hepatitises. Rossiiskaya otorinolaringologiya. 2016;2:73-80. https://doi.org/10.18692/1810-4800-2016-2-73-80