Section: 
School of pharmacotherapy
School of pharmacotherapyThe experience of application of gel preparations containing bacteriophages in the complex therapy of nosocomial rhinosinusitises
L. A. Lazareva (1), V. V. Skibitskii (2), Yu. I. Dorofeeva (1), I. L. Ashuba (1)
(1) State Budgetary Educational Institution of Higher Vocational Education Kuban State Medical University of the Ministry of Healthcare of Russia, Krasnodar, Russia.
(2) State Municipal Health Institution Krasnodar Municipal Hospital of Emergency Medical Care, Krasnodar, Russia
UDK: 616.216.1-002-036.82:615.859
DOI: https://doi.org/10.18692/1810-4800-2017-5-119-127
ABSTRACT
The authors conducted a study of application of gel preparations containing bacteriophages in the complex therapy of nosocomial rhinosinusitises. The preparation was administered at the acute period of the process in the paranasal sinuses in the patients with craniocerebral injuries undergoing artificial pulmonary ventilation. The results of bacteriological studies were assessed all over the supervision period, they made it possible to reveal the trend in the change of the nasal cavity microbial landscape due to reduction of specific weight of the gram-negative flora. The results of preliminary analyses of the clinical observation of the patients with nosocomial rhinosinusitises and the data of X-ray examination suggest the anti-inflammatory effect of the preparation and allow recommending its application in therapeutic and preventive activities.
Publication date:
02.10.2017
Keywords:
nosocomial rhinosinusitis, complex therapy, bacteriophages. For citation:
Lazareva L. A., Skibitskii V. V., Dorofeeva Yu. I., Ashuba I. L. The experience of application of gel preparations containing bacteriophages in the complex therapy of nosocomial rhinosinusitises. Rossiiskaya otorinolaringologiya. 2017;5:119–127. https://doi.org/10.18692/1810-4800-2017-5-119-127