Section: 
Science articles
Science articlesThe efficacy of antiviral therapy in chronic pharyngotonsillitis associated with persistent herpes infection of the oropharynx
N. N. Pirogov (1)
(1) Federal State Budgetary Institution of Higher Vocational Education Tver State Medical University of the Ministry of Healthcare of Russia, Tver, Russia
UDK: 616.321/.322-002.2-085.281-036.8:616.31-022:578.825.11
DOI: https://doi.org/10.18692/1810-4800-2018-1-93-97
ABSTRACT
The article presents the data of the author’s study of prevalence and quantitative identification of herpesviruses, in particular, of Epstein–Barr virus (EBV), cytomegalovirus (CMV) and human herpes virus 6 (HHV-6) by means of real-time polymerase chain reaction (Real-time PCR) in chronic pharyngotongsillitis. The paper provides information about population of microbiota of the pharyngeal mucosa, its quantitative and type-specific assessment and the interrelation between contamination and local viral load of persistent herpesviruses. The author assessed the efficacy of antiviral therapy in chronic pharyngotongsillitis associated with herpes infection in a six months period using control quantitative identification of virus particles by means of real-time PCR, the repeated examination of microbiota of the pharyngeal mucosa, and the control of remission or relapse.
Publication date:
27.12.2017
Keywords:
Epstein–Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus 6 (HHV-6), pharynx mucous membrane, microbiota. For citation:
Pirogov N. N. The efficacy of antiviral therapy in chronic pharyngotonsillitis associated with persistent herpes infection of the oropharynx. Rossiiskaya otorinolaringologiya. 2018;1:93–97. https://doi.org/10.18692/1810-4800-2018-1-93-97