Section: 
Science articles
Science articlesThe state of thioldisulphide system of patients with chronic diseases of upper respiratory tract with concomitant coeliac disease
A. A. Karpov (1), L. S. Oreshko (1), A. N. Pashchinin (1), L. A. Belozerova (2), Z. M. Tskhovrebova (1)
(1) Federal State Budgetary Institution Higher Vocational Education “North-Western State Medical University named after I. I. Mechnikov” of Ministry of Health of the Russian Federation, Saint Petersburg, Russia
(2) Federal State Budgetary Institution of Science Institute for Analytical Instrumentation of the Russian Academy of Sciences, Saint Petersburg, Russia
UDK: 577.158.1:616.211/.232-002.2+616.34-008.1
DOI: https://doi.org/10.18692/1810-4800-2018-2-53-57
ABSTRACT
The article presents the results of the study of thioldisulphide system by amperometric titration method in the patients with chronic diseases of the upper respiratory tract with the concomitant coeliac disease. The study involved 48 patients with genetically confirmed diagnosis of celiac disease, aged 19 to 45 years. We observed a significant reduction of thioldisulphide index (the ratio of the concentration of SH-and-SS-groups of blood serum), which indicates the resistance tissue disorder and the intensification of free radical oxidation in these patients. The change of TDI may serve as a diagnostic criterion of the efficacy of the therapy.
Publication date:
02.04.2018
Keywords:
thioldisulphide system, coeliac disease. For citation:
Karpov A. A., Oreshko L. S., Pashchinin A. N., Belozerova L. A., Tskhovrebova Z. M. The state of thioldisulphide system of patients with chronic diseases of upper respiratory tract with concomitant coeliac disease. Rossiiskaya otorinolaringologiya. 2018;2:53–57. https://doi.org/10.18692/1810-4800-2018-2-53-57