Section: 
Science articles
Science articlesThe present-day views of the role of palatine tonsils in the immune system and analysis of application of immunotropic drugs in chronic tonsillitis
E. L. Savlevich (1), V. S. Kozlov (1), I. B. Angotoeva (2)
(1) Central State Medical Academy, Department for Presidential Affairs of the Russian Federation, Moscow, 121359, Russia
(2) Russian Medical Academy of Continuing Postgraduate Education, Moscow, 123242, Russia
UDK: 616.322:612.017.1+616.322-002.2:615.37
DOI: https://doi.org/10.18692/1810-4800-2018-6-48-55
ABSTRACT
Palatine tonsils, due to their topographic position, are first exposed to the attack of various pathogens, they act as the first line of defense and are an important component of the oropharynx MALT (mucosa-associated lymphoid tissue)-system. Tonsillar cells actively participate both in congenital and in induced humoral and cellular immune responses. There are a great number of various immunological tests and proposals for conservative treatment of chronic tonsillitis (CT). This review analyzes the studied changes in the immunological parameters of the mucous membrane of the oropharynx and systemic immunity, and the use of immunotropic drugs in CT. Currently, there is no single concept of both laboratory parameters of palatine tonsils in normal condition and in inflammation, and of the therapeutic way of correction thereof, especially on the local immunity level.
Publication date:
06.12.2018
Keywords:
chronic tonsillitis, immunity, immunomodulators, MALT-system, lymphocytes. For citation:
Savlevich E. L., Kozlov V. S., Angotoeva I. B. The present-day views of the role of palatine tonsils in the immune system and analysis of application of immunotropic drugs in chronic tonsillitis. Rossiiskaya otorinolaringologiya. 2018;6:48–55. https://doi.org/10.18692/1810-4800-2018-6-48-55