Section: 
Science articles
Science articlesThe management of adult patients with mucoviscidosis associated with polypous rhinosinusitis
V. M. Svistushkin (1), E. L. Amelina (2), G. L. Shumkova (1), S. A. Krasovskii (2), E. V. Sin’kov (1)
(1) I. M. Sechenov First Moscow State Medical University, Ministry of Healthcare of the Russian Federation (Sechenov University), Moskow, 119991, Russia
(2) Research Institute of Pulmonology, Federal Medico-Biological Agency of Russia, Moscow, 101000, Russia
UDK: 616.216.1-002-006.5-031.81-053.8-08
DOI: https://doi.org/10.18692/1810-4800-2018-6-56-63
ABSTRACT
Polypous rhinosinusitis (PRS) is the predominant ENT disorder in the patients with mucoviscidosis. It may occur in 8 months old children and soon become a chronic condition. The congestion of infected thick mucus in paranasal sinuses and the nasal breathing obstruction worsen the severity of the patients’ condition. Therefore, timely examination and treatment of PRS in the form of restoration of paranasal sinus aeration and mucociliary clearance are necessary to overcome the chronic infection of the upper respiratory tract. In surgical treatment, the expanded functional endoscopic sinus surgery (FESS) is the method of choice. This method provides the preservation of facial skull anatomy and the drainage of paranasal sinuses. Polypous rhinosinusitis in the patients with mucoviscidosis often recurs. Therefore, such patients need lifelong follow up by an ENT doctor and the conservative treatment of polypous rhinosinusitis. Topical mucolytic and antibacterial therapy is also necessary. Compression inhalator with the mode for paranasal sinuses may serve as a method of medications delivery.
Publication date:
06.12.2018
Keywords:
mucoviscidosis, polypous rhinosinusitis, pathogenesis, inhaled antibiotics, dornase alfa, polypotomy. For citation:
Svistushkin V. M., Amelina E. L., Shumkova G. L., Krasovskii S. A., Sin’kov E. V. The management of adult patients with mucoviscidosis associated with polypous rhinosinusitis. Rossiiskaya otorinolaringologiya. 2018;6:56–63. https://doi.org/10.18692/1810-4800-2018-6-56-63