Section: 
General questions of otolaryngology
General questions of otolaryngologyExperimental study of remote action of 445 nm semiconductor laser on biological model
Yu. S. Aleksanyan (1), G. P. Zakharova (2), A. A. Krivopalov (3)
(1), (2), (3) Saint Petersburg Institute of Ear, Throat, Nose and Speech, Saint Petersburg, 190013, Russian Federation, (3) Mechnikov North-Western State Medical University, Saint Petersburg, 191015, Russian Federation
UDK: УДК 615.849.19:616-092.4
DOI: https://doi.org/10.18692/1810-4800-2025-4-8-12
ABSTRACT
Abstract. Currently, despite a wide range of high-tech methods for treating patients with chronic rhinitis, the prevalence of the disease remains quite high. In this regard, to improve the effectiveness of surgical treatment of nasal obstruction, the analysis of the features of the use of various laser systems and the development of adequate methods and modes of their action are of undoubted relevance. Objective. To study the effect of a semiconductor laser with a wavelength of 445 nm on experimental tissue samples in a constant mode with remote exposure. Material and methods. We conducted a study to analyze the superficial remote effect of a semiconductor laser with a wavelength of 445 nm on an experimental sample of pig liver tissue. The effect of eight laser radiation power indicators was studied: from 0.5 to 4.0 W with a step of 0.5 W. The study was carried out at a distance from the radiation source to the sample surface of 3 mm, 5 mm, 10 mm. The exposure time in continuous mode was from 3 to 10 seconds for point exposure and the speed of movement was 2 mm/s for the linear exposure in the remote method. Results. The data obtained indicate that in the range of exposure power from 1.5 to 2.5 W at a distance of 10 mm from the object the most pronounced coagulation effect without destruction areas is observed. Conclusion. The obtained data of the experimental study indicate that with the remote method of exposure, both in point and linear constant modes, the semiconductor laser with a wavelength of 445 nm has a pronounced coagulation effect. The optimal expression of the coagulation zone without excessive tissue necrosis is observed at a power of 1.5 to 2.5 W at a distance of 10 mm from the radiation source to the study object in point and linear constant modes. The obtained results indicate the possibility of using this method and mode when using the gentlest approach to surgical intervention on the inferior nasal turbinates.
Publication date:
13.08.2025
Keywords:
laser surgery, laser radiation power 445 nm, experimental study, biological tissue For citation:
Aleksanyan Yu. S., Zakharova G. P., Krivopalov A. A. Experimental study of remote action of 445 nm semiconductor laser on biological model. Russian Otorhinolaryngology. 2025;24(4):8-12. (In Russ.) https://doi.org/10.18692/1810-4800-2025-4-8-12