Section: 
Otiology
OtiologyMeta-analysis of hearing impairments in children with congenital heart defects and ocular pathology
N. A. Daikhes (1), V. S. Basyuk (2), A. S. Machalov (3), S. B. Lazurenko (4), K. A. Oganyan (5)
(1), (3), (5) National Medical Research Center of Otorhinolaryngology of FMBA of Russia, Moscow, 123182, Russian Federation, (1), (3) Pirogov Russian National Research Medical University, Moscow, 117513, Russian Federation, (2) Lomonosov Moscow State University, Moscow, 119234, Russian Federation, (2), (4) Russian Academy of Education, Moscow, 119121, Russian Federation, (3) Russian Medical Academy of Continuous Professional Education, Moscow, 123242, Russian Federation, (4) National Medical Research Center for Children's Health, Moscow, 119991, Russian Federation, (4) Institute of Special Education, Moscow, 119121, Russian Federa
UDK: УДК 616.28-009-053.1:616.12-007.2+617.75:519.23
DOI: https://doi.org/10.18692/1810-4800-2026-1-101-109
ABSTRACT
Abstract. Introduction. Congenital heart defects and ocular pathology occupy a significant place in the structure of childhood morbidity, while comorbid hearing impairments in these groups remain epidemiologically understudied. Objective. To estimate the prevalence of comorbid hearing impairment in children with congenital heart defects and ocular pathology in children with sensorineural hearing loss. Materials and methods. A systematic review and meta-analysis of 8 studies (n=1062 patients) selected from PubMed, eLibrary, Scopus, and Cochrane Library databases was conducted. The search period was limited from 2000 to 2025. Due to the anticipated high heterogeneity of studies, attributed to differences in populations and diagnostic methods, the pooled prevalence was calculated using the DerSimonian-Laird random-effects model. Heterogeneity between studies was quantitatively assessed using the I? statistic. Forest plots were constructed to visualize the meta-analysis results. Results. The meta-analysis revealed that 28% (95% CI: 22–35%) of children with hearing loss have concomitant ocular pathology. The pooled prevalence of sensorineural hearing loss in patients with congenital heart defects was 26% (95% CI: 13–42%). Conclusions. Hearing impairment is a widespread comorbid pathology in children with congenital developmental anomalies. The obtained data confirm the advisability of implementing mandatory audiological monitoring and an interdisciplinary approach to managing these patient groups.
Publication date:
24.02.2026
Keywords:
sensorineural hearing loss, children, congenital heart defects, ocular pathology, comorbidity, meta-analysis For citation:
Daikhes N. A., Basyuk V. S., Machalov A. S., Lazurenko S. B., Oganyan K. A. Meta-analysis of hearing impairments in children with congenital heart defects and ocular pathology. Russian Otorhinolaryngology. 2026;25(1):101-109. (In Russ.) https://doi.org/10.18692/1810-4800-2026-1-101-109