Section: 
General questions of otolaryngology
General questions of otolaryngologyAnalysis of species composition of the microbiota in inflammatory diseases of ent organs
A. E. Stavskii (1), E. A. Stavskii (2)
(1) United Medical Corporation Clinic, Novosibirsk, 630005, Russian Federation, (2) Novosibirsk State Medical University, Novosibirsk, 630091, Russian Federation
UDK: УДК 616.211/.232-008.87:579.8
DOI: https://doi.org/10.18692/1810-4800-2026-1-8-15
ABSTRACT
Abstract. Acute and chronic inflammatory diseases of the ENT organs of bacterial and viral etiology are one of the most important problems of national and international healthcare. In particular, patients complaining of discomfort and sore throat account for almost a third of all outpatients. The incidence of rhinitis, sinusitis, and chronic tonsillitis in the population is 10-40, 5-15 and 15-25%, respectively. In outpatient practice, CR can account for from 4 to 35%. Objective. To analyze the species composition of microflora colonizing the mucous membrane of the nose, nasopharynx, and oropharynx in patients with inflammatory diseases of the ENT organs. Patients and methods. The study included 450 patients with inflammatory diseases of the ENT organs; of these, 151 were men (33.5%), 151 were women (33.5%), and 148 were children (33%). Results. 44 microbiota species were identified. These were present in 65.7% of cases as monocultures and in 34.3% of cases as part of polycomponent microbial associations. Monocultures of normobiota were detected in 18.6% of cases. Opportunistic microflora accounted for 61.5% (including staphylococci — 54.3%; streptococci — 11.7%); respiratory pathogens — 7.1%; and representatives of other pathogenic microflora — 6.9%. In 20% of cases, monocultures of coagulase-negative staphylococci (CoNS) were detected. In young children (under 3 years of age), the detection rate of Staphylococcus aureus in the mucosal microbiota was 28.2%, with etiologically significant numbers reaching 7.7%. Respiratory pathogens were identified in 19.2% of children, and intestinal pathogens in 1.3%. In addition, in the same patients (both children and adults), the simultaneous presence of microbiota representatives differing in species and quantitative composition in the mucosa of different sections of the upper respiratory tract was detected in 17.3% of cases.
Publication date:
24.02.2026
Keywords:
microbiota, species composition, bacteria, ENT organs, mucous membrane of the nose, nasopharynx and oropharynx For citation:
Stavskii A. E., Stavskii E. A. Analysis of species composition of the microbiota in inflammatory diseases of ent organs. Russian Otorhinolaryngology. 2026;25(1):8-15. (In Russ.) https://doi.org/10.18692/1810-4800-2026-1-8-15